Properties
Description
KW-2478, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 574.66, and its molecular formula is C30H42N2O9. It targets the HSP90.
Molecular Formula
C30H42N2O9
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 114 mg/mL (198.37 mM); Water: insoluble; Ethanol: 3 mg/mL (5.22 mM); In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 9 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
KW-2478 plays a key role in disrupting the function of Hsp90, which is critical for the stability and function of many cancer-associated proteins.
