Properties
Description
PF-04929113, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 521.5, and its molecular formula is C25H30F3N5O4. It targets the HER2 and HSP90.
Molecular Formula
C25H30F3N5O4
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 90 mg/mL (172.57 mM); Water: insoluble; Ethanol: 4 mg/mL (7.66 mM); In vivo: 0.5% CMC + 0.25% Tween 80, 23 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
PF-04929113 can be studied extensively for its potential therapeutic applications in the treatment of chronic lymphocytic leukemia (CLL) and other B-cell malignancies.
