HSP inhibitor, XL-888, Purity ≥98%

Synonym: 1149705-71-4; XL888; XL-888; XL 888; 2-[[(2R)-Butan-2-yl]amino]-4-N-[(1S,5R)-8-[5-(cyclopropanecarbonyl)pyridin-2-yl]-8-azabicyclo[3.2.1]octan-3-yl]-5-methylbenzene-1,4-dicarboxamide; HSP inhibitor

CAS Number: 1149705-71-4
Compound CID: 60147023

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

XL-888, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 503.63, and its molecular formula is C₂₉H₃₇N₅O₃. It targets the HSP90.

Molecular Weight

503.63

Molecular Formula

C₂₉H₃₇N₅O₃

Targets

HSP90

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 99 mg/mL (196.56 mM); Water: insoluble; Ethanol: insoluble; In vivo: 30% PEG400 + 0.5% Tween80 + 5% propylene glycol,28 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

XL-888 plays a key role in reducing tumor growth and improving patient outcomes in cancers like melanoma and non-small cell lung cancer.