Properties
Description
Penciclovir, soluble in DMSO and water and insoluble in ethanol, hinders the replication of the herpes simplex virus. It targets HSV-1 and HSV-2.
Molecular Formula
C10H15N6O3
Targets
HSV-1: 0.5 μg/mL (EC50); HSV-2: 0.8 μg/mL (EC50)
Solubility
DMSO: 30 mg/mL (118.45 mM); Water: 1 mg/mL (3.94 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Penciclovir is employed in the investigation of antiviral mechanisms against herpes simplex virus (HSV), focusing on its efficacy in inhibiting DNA synthesis within infected cells.