Advantages of High-Throughput Glycan Screening Using UHPLC-FLD

High-performance liquid chromatography with fluorescence detection (HPLC-FLD) combines ultra-high-performance liquid chromatography (HPLC) and fluorescence detection (FLD) to enable rapid separation as well as an accurate analysis of glycan from complex mixtures. With the increasing importance of sugars in life sciences, the need for high-throughput glycan screening is becoming more and more urgent. The traditional analysis methods for glycan have problems such as long time, complicated operation, and low detection sensitivity, which have been solved by the emergence of HPLC-FLD technology. The advantages of this technology are its strong separation ability, fast analysis speed, and high detection sensitivity, which can simultaneously detect a variety of glycan components and quantitatively analyze their contents. In recent years, the development of automated sample processing and data analysis methods has also supported high-throughput glycan screening. Therefore, the current development of high-throughput glycan screening using HPLC-FLD indicates that this technology has a promising application in the field of glycan analysis.

High-Throughput Glycan Screening Using UHPLC-FLD at CD BioGlyco

CD BioGlyco is a biotech company focused on the development of glycan analysis and screening platforms. We are committed to providing our clients with high-throughput glycan screening services to facilitate the development and production of glycan-related products. We offer the services following:

• High-throughput structural analysis services of glycans using UHPLC-FLD
  This equipment enables fast and efficient isolation and analysis of complex sugar mixtures. The high pressure and small particle size packing of UHPLC allows for higher resolution, while the fluorescence detector allows for the detection of glycans by specific fluorescent markers with high sensitivity and selectivity.
• High-throughput glycan quantification services using UHPLC-FLD
  We offer high throughput quantification of glycans using UHPLC-FLD. We optimize the separation parameters and detection conditions to achieve quantitative glycan analysis of large-volume samples.
• High-throughput molecular weight analysis services of glycans using UHPLC-FLD

Fig.1 UHPLC-FLD-based glycan analysis. (CD BioGlyco)

Applications

• Glycan quality control and drug analysis
• Discovery of glycan biomarkers associated with a disease or physiologic states
• New materials with specific properties

Advantages of Us

• Accurate and efficient analysis tools
• Experienced experts
• Flexible services to meet client needs

CD BioGlyco is committed to providing high-quality high-throughput glycan screening services using UHPLC-FLD. Our professional team, advanced equipment, and strict quality control have equipped us to provide satisfactory products and services to our clients. If you are interested in our services, please contact us for more details.