Your Most Reliable Human Thrombin Evaluation Partner

Whether you want to analyze Pharmaceutical, Biological, or Pharmaceutical Excipient, our professional and well-trained Pharmaceutical and Biological Analysis team provides you with the most satisfactory solution. Human thrombin is a serine protease and plays a role in blood clotting. We provide professional human thrombin and human prothrombin complex evaluation services.

• Human thrombin bulk and final bulk analysis
  • Basic test: We provide rapid and accurate pH testing, protein content testing, specific activity analysis, and sterility testing.
  • Human thrombin potency: After diluting the human thrombin standard and the samples to be tested separately, we test the agglutination time in parallel with an automated hemagglutination meter. The potency in the samples is calculated according to the linear regression equation.
• Human thrombin final product analysis
  • Identification
    • We use a double immunodiffusion assay for the rapid identification of human thrombin, which produces precipitation lines only with anti-human sera or plasma, but not with other (e.g., anti-horse, anti-bovine, anti-pig, anti-goat) sera or plasma.
    • We use liquid chromatography, tandem mass spectrometry (LC-MS/MS), and colorimetric assay to rapidly identify human thrombin.
  • Basic test: Our efficient analytical team offers a range of basic and simple analyses including pH test, vacuum test, reconstitution time test, deliverable volume test, and moisture measurement.
  • Content test
    • Sodium ion and calcium ion content: We use an ion detector or flame photometric method to determine the ion content of the sample.
    • Sugar content and glycine content: We provide professional quantitative analysis of sugar content and glycine content by high-performance liquid chromatography (HPLC).
    • Residue: Based on the characteristics of the residues, we use colorimetry to determine the polyethylene glycol content and polysorbate 80 content. Moreover, we accurately quantify tributyl phosphate by gas chromatography (GC).

Publication Data

Applications of Human Thrombin Evaluation

• Comprehensive human thrombin evaluation facilitates the design and development of safer and more effective thrombin drugs.
• Comprehensive human thrombin evaluation provides a basis for animal-derived thrombin evaluation.
• Comprehensive human thrombin evaluation plays an important role in the development of analytical methods for bovine thrombin, human thrombin, recombinant thrombin, and fibrin glue.

Advantages of Us

• Based on the client's analytical needs, our professional valuation team provides customized biological evaluation solutions.
• Whether you need to analyze bulk, final bulk or a finished human thrombin, our excellent service team provides you with the most convenient service.
• We have state-of-the-art analytical systems and experienced staff to ensure the best possible results.

Based on many years of analyzing experience, CD BioGlyco provides precise and high-quality pharmaceutical and biological analysis services to clients. Our efficient service has been praised by our clients all over the world. We're here to assist you, so please don't hesitate to contact us.