Unveiling the Secrets of Hyaluronan with Precision Analysis

Hyaluronan plays multiple roles as a pharmaceutical excipient in drug formulations. It not only improves the stability and viscosity of formulations, but also serves as a lubricant, humectant, and carrier for drugs. It helps to improve the texture of formulations, enhance the bioavailability of drugs, and show potential in the field of tissue repair and regenerative medicine. CD BioGlyco offers a comprehensive range of Pharmaceutical Excipient Analysis Services, including our tailored hyaluronan analysis service.

• By utilizing mass spectrometry (MS), nuclear magnetic resonance (NMR), and infrared spectroscopy (IR), we determine the chemical composition and structure of hyaluronan and verify its purity and quality for our clients.

Fig.1 Chemical structure of hyaluronan. (Valachov, et al., 2024)

• We analyze the physical properties, such as viscosity, solubility, and gelation ability, using instruments like viscometers and rheometers. These properties are crucial for the application of hyaluronan in pharmaceutical preparations and provide a scientific basis for your drug development.
• CD BioGlyco offers professional hyaluronan microbiological testing services, utilizing advanced technology to ensure accurate and reliable test results. Our comprehensive microbiological testing covers total colony count, mold, and yeast to meet the diverse needs of our clients for microbial contamination.
• Compatibility analysis of hyaluronan is performed with human tissues through in vitro cellular experiments, animal experiments, and immunological analysis. In cellular experiments, we contact hyaluronan with different types of human cells to observe its effect on cell growth and function. In animal experiments, we select appropriate animal models for testing and observe the effects of hyaluronan on animal tissues and organs. We hope that these multifaceted and comprehensive analytical methods will provide you with a more accurate assessment of the possible risks posed by the drug.
• Our experts assess the impact of various environmental conditions, including temperature, humidity, light, and other factors, on the stability of hyaluronan. We hope to offer advice and support through the analysis report in determining the most suitable storage and usage conditions for your drug research.

Applications

• The analytical techniques are used to evaluate biomaterials related to tissue engineering and regenerative medicine, such as carrier materials for repairing cartilage and soft tissue.
• Hyaluronan analysis can be utilized to evaluate the architecture, durability, and compatibility with living organisms of biomaterials, as well as the impact of cellular interactions.
• Hyaluronan analytical techniques can be employed to evaluate the hyaluronan content, molecular weight distribution, and mass properties of a product to guarantee its quality and effectiveness.

Advantages

• Our analysis technology is used in a variety of fields such as pharmaceuticals, biomedicine, biomaterials, and cosmetics for different types of samples and applications.
• We employ a variety of analytical methods to thoroughly evaluate the composition and properties of samples from diverse viewpoints.
• CD BioGlyco offers a diverse array of analytical techniques for you to choose from, allowing you to select the most suitable method for your analysis based on your specific requirements.

CD BioGlyco offers thorough hyaluronan analysis services, including but not limited to structural identification, purity analysis, and stability studies. Additionally, we provide a range of analytical solutions tailored to different sample types and applications to meet the diverse needs of clients in hyaluronan analysis. Please feel free to contact us for more information.