Hydroxylase inhibitor, Ro 61-8048, Purity ≥98%

Synonym: 199666-03-0; Ro61-8048; 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-benzenesulfonamide; 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide; 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide; Hydroxylase inhibitor

MDL: MFCD11040807
CAS Number: 199666-03-0
Compound CID: 5282337

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Ro 61-8048, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting hydroxylases. The molecular weight of the compound is 421.45, and its molecular formula is C₁₇H₁₅N₃O₆S₂. It targets the KMO and KMO.

Molecular Weight

421.45

Molecular Formula

C₁₇H₁₅N₃O₆S₂

Targets

KMO

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 80 mg/mL (189.82 mM); Water: insoluble; Ethanol: insoluble; In vivo: 2% DMSO + 30% PEG 300 + 5% Tween 80 + ddH₂O, 9 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Ro 61-8048 plays a key role in inducing cell cycle arrest and apoptosis in cancer cells.