Properties
Description
Hydroxyurea, soluble in DMSO and water and insoluble in ethanol, is an antineoplastic agent that inhibits DNA synthesis. The molecular weight of the compound is 76.05, and its molecular formula is CH4N2O2.
Molecular Formula
CH4N2O2
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 14 mg/mL (184.08 mM); Water: 14 mg/mL (184.08 mM); Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Hydroxyurea can be studied extensively for its potential therapeutic applications in the treatment of chronic myelogenous leukemia (CML) and essential thrombocythemia.