Properties
Description
ICI-118551, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets β1-adrenergic receptor, β2-adrenergic receptor, and β3-adrenoceptor.
Molecular Formula
C17H27NO2·HCl
Targets
β1-adrenergic receptor: 49.5nM (Ki); β2-adrenergic receptor: 0.7nM (Ki); β3-adrenoceptor: 611nM (Ki)
Solubility
DMSO: 59 mg/mL (187.98 mM); Water: 20 mg/mL (63.71 mM); Ethanol: 59 mg/mL (187.98 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
ICI-118551 can be used for its beta-adrenergic receptor blocking activity.
Storage
Store at -20°C, and keep desiccated.
