IDO inhibitor, BMS-986205, Purity ≥98%

Synonym: 1923833-60-6; BMS 986205; BMS986205; ONO-7701; ONO 7701; ONO7701; F-001287; F001287; F001287; Linrodostat; (2R)-N-(4-Chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamide; IDO inhibitor

CAS Number: 1923833-60-6
Compound CID: 121328278

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BMS-986205, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting IDO. The molecular weight of the compound is 410.91, and its molecular formula is C₂₄H₂₄ClFN₂O. It targets the IDO1.

Molecular Weight

410.91

Molecular Formula

C₂₄H₂₄ClFN₂O

Targets

IDO1

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 74 mg/mL (180.08 mM); Water: insoluble; Ethanol: 74 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

BMS-986205 can be used for its ability to disrupt the immune evasion mechanisms employed by tumors through IDO1 activity, thereby enhancing anti-tumor immunity.