Properties
Description
INCB024360 analog, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting IDO. The molecular weight of the compound is 271.63, and its molecular formula is C9H7ClFN5O2. It targets the IDO1.
Molecular Formula
C9H7ClFN5O2
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 46 mg/mL (169.34 mM); Water: insoluble; Ethanol (warmed): 46 mg/mL (169.34 mM); In vivo: 5% DMSO + 45% PEG 300 + ddH2O 20 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
INCB024360 analog can be used for its ability to evaluate its effectiveness in managing tumors with IDH1 mutations.
