Properties
Description
Indoximod, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting IDO. The molecular weight of the compound is 218.25, and its molecular formula is C12H14N2O2.
Molecular Formula
C12H14N2O2
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 1 mg/mL (4.58 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 30% PEG 300 + 5% Tween 80 + ddH2O, 0.1 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Indoximod plays a key role in blocking the IDO1 enzyme, which plays a role in immune suppression within the tumor microenvironment, thereby enhancing anti-tumor immune responses.
