(E)-3-(1-((2R, 4S, 5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-5-yl)-N-(6-(2, 2, 2-trifluoroacetamido)hexyl)acrylamide

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Cat. No.: X24-03-LY045

(E)-3-(1-((2R, 4S, 5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-5-yl)-N-(6-(2, 2, 2-trifluoroacetamido)hexyl)acrylamide

Synonym: 252337-59-0; (5'-O-(Dimethoxytrityl)-5-[N-(6-(trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2'-deoxyuridine)

CAS Number: 252337-59-0
PubChem CID: 15484915

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

(E)-3-(1-((2R, 4S, 5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-5-yl)-N-(6-(2, 2, 2-trifluoroacetamido)hexyl)acrylamide is a TFA-modified nucleoside containing tetracycline and acrylamide groups in its structure.

Molecular Weight

794.81

Molecular Formula

C₄₁H₄₅F₃N₄O₉

Form

White to off-white solid

Purity

≥98%

Applications

(E)-3-(1-((2R, 4S, 5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-5-yl)-N-(6-(2, 2, 2-trifluoroacetamido)hexyl)acrylamide has potential antitumor activity and inhibits tumor growth by interfering with the proliferation and metastasis of tumor cells.

Storage

Store at -20°C.

Safety Information

Personal Protective Equipment

Gloves, eyeshields, N95 mask