Properties
Description
AG-1024, soluble in DMSO and insoluble in ethanol and water, blocks the insulin-like growth factor 1 receptor (IGF-1R) signaling pathway, which plays a crucial role in cell growth and survival. It targets IGF-1R and Insulin receptor.
Molecular Formula
C14H13BrN2O
Targets
IGF-1R: 7 nM; Insulin receptor: 57 nM
Solubility
DMSO: 59 mg/mL (193.33 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AG-1024 is applied to study the inhibition of IGF-1 receptor signaling, important in cancer research targeting growth factor pathways.
