IGF-1R inhibitor AZD3463, Purity ≥98%

Synonym: 1356962-20-3; IGF-1R inhibitor; AZD 3463; AZD-3463

CAS Number: 1356962-20-3
Compound CID: 56599293

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD3463, soluble in DMSO and insoluble in ethanol and water, blocks the insulin-like growth factor 1 receptor (IGF-1R) signaling pathway, which plays a crucial role in cell growth and survival. It targets ALK.

Molecular Weight

448.95

Molecular Formula

C₂₄H₂₅ClN₆O

Targets

ALK: 0.75 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 22 mg/mL (49 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD3463 is used in research to block IGF-1 receptor, which plays a significant role in developing anti-cancer treatments.