IGF-1R inhibitor PQ 401, Purity ≥98%

Synonym: 196868-63-0; IGF-1R inhibitor; PQ401

MDL: MFCD00160558
CAS Number: 196868-63-0
Compound CID: 9549305

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PQ 401, soluble in DMSO and insoluble in ethanol and water, blocks the insulin-like growth factor 1 receptor (IGF-1R) signaling pathway, which plays a crucial role in cell growth and survival. It targets IGF-1R.

Molecular Weight

341.79

Molecular Formula

C₁₈H₁₆ClN₃O₂

Targets

IGF-1R: <1 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 30 mg/mL (87.77 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PQ 401 is used to understand IGF-1 receptor inhibition and its potential therapeutic applications in cancer.