IKK/IκB inhibitor Amlexanox, Purity ≥98%

Synonym: amlexanox; 68302-57-8; Amoxanox; Aphthasol; 2-Amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid; Amlenanox; Elics; IKK/IκB inhibitor

MDL: MFCD00864790
CAS Number: 68302-57-8
Compound CID: 2161

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Amlexanox, soluble in DMSO and ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKKε and TBK1.

Molecular Weight

298.29

Molecular Formula

C₁₆H₁₄N₂O₄

Targets

IKKε: 12 μM; TBK1: 12 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 54 mg/mL (181.03 mM); Water: Insoluble; Ethanol: <1 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Amlexanox can be used to investigate its anti-inflammatory and anti-allergic activities through the inhibition of IKKε and TBK1.

Storage

Store at -20ºC.