IKK/IκB inhibitor AZD3264, Purity ≥98%

Synonym: AZD3264; 1609281-86-8; AZD-3264; 2TT3S8GPB7; AZD 3264 [WHO-DD]; 3-Thiophenecarboxamide, 2-((aminocarbonyl)amino)-5-(4-(3,5-dimethyl-4-isoxazolyl)-2-((3S)-3-pyrrolidinyloxy)phenyl)-; (S)-5-(4-(3,5-Dimethylisoxazol-4-yl)-2-(pyrrolidin-3-yloxy)phenyl)-2-ureidothiophene-3-carboxamide; IKK/IκB inhibitor

CAS Number: 1609281-86-8
Compound CID: 91666658

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD3264, soluble in DMSO and warmed ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK2.

Molecular Weight

441.5

Molecular Formula

C₂₁H₂₃N₅O₄S

Targets

IKK2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (169.88 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL (4.53 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZD3264 can be used to evaluate its efficacy as an IKK2 inhibitor in preclinical models of inflammation and cancer.

Storage

Store at -20ºC.