IKK/IκB inhibitor AZD3264, Purity ≥98%

Synonym: AZD3264; 1609281-86-8; AZD-3264; 2TT3S8GPB7; AZD 3264 [WHO-DD]; 3-Thiophenecarboxamide, 2-((aminocarbonyl)amino)-5-(4-(3,5-dimethyl-4-isoxazolyl)-2-((3S)-3-pyrrolidinyloxy)phenyl)-; (S)-5-(4-(3,5-Dimethylisoxazol-4-yl)-2-(pyrrolidin-3-yloxy)phenyl)-2-ureidothiophene-3-carboxamide; IKK/IκB inhibitor

CAS Number: 1609281-86-8
Compound CID: 91666658

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD3264, soluble in DMSO and warmed ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK2.

Molecular Weight

441.5

Molecular Formula

C₂₁H₂₃N₅O₄S

Targets

IKK2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (169.88 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL (4.53 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD3264 can be used to evaluate its efficacy as an IKK2 inhibitor in preclinical models of inflammation and cancer.