IKK/IκB inhibitor Bardoxolone methyl, Purity ≥98%

Synonym: Bardoxolone methyl; 218600-53-4; CDDO-Me; CDDO methyl ester; RTA 402; NSC 713200; CDDO-Methyl ester; IKK/IκB inhibitor

CAS Number: 218600-53-4
Compound CID: 400769

Product Size

25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bardoxolone methyl, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK.

Molecular Weight

505.7

Molecular Formula

C₃₂H₄₃NO₄

Targets

IKK

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 21 mg/mL (41.52 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Bardoxolone methyl can be used to investigate its antioxidant and anti-inflammatory properties via activation of Nrf2 in chronic kidney disease and cancer research.

Storage

Store at -20ºC.