Cat. No.: X23-10-ZQ754
IKK/IκB inhibitor Bardoxolone, Purity ≥98%
Synonym: Bardoxolone; CDDO; 218600-44-3; RTA 401; RTA-401; (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-Cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicene-4a-carboxylic acid; 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid; IKK/IκB inhibitor
- MDL: MFCD07772296
- CAS Number: 218600-44-3
- Compound CID: 400010
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Bardoxolone, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses.
Molecular Formula
C31H41NO4
Solubility
DMSO: 5 mg/mL (10.17 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Bardoxolone can be utilized to study its effects on oxidative stress and inflammation through Nrf2 pathway activation.
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