Cat. No.: X23-10-ZQ754
IKK/IκB inhibitor Bardoxolone, Purity ≥98%
Synonym: Bardoxolone; CDDO; 218600-44-3; RTA 401; RTA-401; (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-Cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicene-4a-carboxylic acid; 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid; IKK/IκB inhibitor
- MDL: MFCD07772296
- CAS Number: 218600-44-3
- Compound CID: 400010
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Bardoxolone, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses.
Molecular Formula
C31H41NO4
Solubility
DMSO: 5 mg/mL (10.17 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Bardoxolone can be utilized to study its effects on oxidative stress and inflammation through Nrf2 pathway activation.
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