Properties
Description
BMS-345541 HCl modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK1 and IKK2.
Molecular Formula
C14H18ClN5
Targets
IKK1: 4 μM; IKK2: 0.3 μM
Identity
Confirmed by NMR/HPLC/MS.
Applications
BMS-345541 HCl can be used to explore its selective inhibition of IκB kinase (IKK) to modulate NF-κB signaling in inflammatory and autoimmune diseases.