IKK/IκB inhibitor BMS-345541, Purity ≥98%

Synonym: 445430-58-0; BMS-345541; BMS-345541 free base; BMS345541; N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine; IKK Inhibitor III, BMS-345541; IKK Inhibitor III; IKK/IκB inhibitor

CAS Number: 445430-58-0
Compound CID: 9813758

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BMS-345541, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK1 and IKK2.

Molecular Weight

255.32

Molecular Formula

C₁₄H₁₇N₅

Targets

IKK1: 4 μM; IKK2: 0.3 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 8 mg/mL (31.32 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

BMS-345541 can be explored as a selective IκB kinase inhibitor to understand its role in modulating NF-κB signaling in inflammatory and autoimmune disease research.