IKK/IκB inhibitor IKK-16, Purity ≥98%

Synonym: 873225-46-8; IKK Inhibitor VII; IKK 16; IKK-16; IKK16; IKK-16 (IKK Inhibitor VII); IKK-16 (free base); IKK/IκB inhibitor

MDL: MFCD23704180
CAS Number: 873225-46-8
Compound CID: 9549298

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IKK-16, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK complex, IKK1, and IKK2.

Molecular Weight

483.63

Molecular Formula

C₂₈H₂₉N₅OS

Targets

IKK complex: 70 nM; IKK1: 200 nM; IKK2: 40 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 95 mg/mL (196.42 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

IKK-16 can be studied for its specific inhibition of IKK-1 and IKK-2 in modulating the NF-κB signaling pathway.

Storage

Store at -20ºC.