IKK/IκB inhibitor IKK-2 inhibitor VIII, Purity ≥98%

Synonym: IKK-2 Inhibitor VIII; 406209-26-5; ACHP (Hydrochloride); ACHP Hydrochloride; 2-Amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-(piperidin-4-yl)nicotinonitrile hydrochloride; 2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-piperidin-4-ylpyridine-3-carbonitrile; Hydrochloride; IKK/IκB inhibitor

CAS Number: 406209-26-5
Compound CID: 136216943

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IKK-2 inhibitor VIII modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKKα and IKKβ.

Molecular Weight

400.9

Molecular Formula

C₂₁H₂₅ClN₄O₂

Targets

IKKα: 250 nM; IKKβ: 8.5 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

IKK-2 inhibitor VIII can be employed to investigate its selective inhibition of IKK-2 in the NF-κB pathway in inflammatory disease models.

Storage

Store at -20ºC.