IKK/IκB inhibitor IMD 0354, Purity ≥98%

Synonym: IMD-0354; 978-62-1; IMD 0354; N-(3,5-Bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide; IKK-2 Inhibitor V; IMD0354; N-[3,5-Bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide; IKK/IκB inhibitor

MDL: MFCD00218820
CAS Number: 978-62-1
Compound CID: 5081913

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IMD 0354, soluble in DMSO and ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKKβ.

Molecular Weight

383.67

Molecular Formula

C₁₅H₈ClF₆NO₂

Targets

IKKβ

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (23.45 mM); Water: Insoluble; Ethanol: 72 mg/mL (187.66 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

IMD 0354 can be employed to investigate its role as a selective IKK-β inhibitor in studies related to inflammation and immune response.

Storage

Store at -20ºC.