IKK/IκB inhibitor INH14, Purity ≥98%

Synonym: INH14; 1-(4-Ethylphenyl)-3-phenylurea; 200134-22-1; N-(4-Ethylphenyl)-N'-phenylurea; 3-(4-Ethylphenyl)-1-phenylurea; IKK/IκB inhibitor

MDL: MFCD00158246
CAS Number: 200134-22-1
Compound CID: 295048

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

INH14, soluble in DMSO and ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKKα and IKKβ.

Molecular Weight

240.3

Molecular Formula

C₁₅H₁₆N₂O

Targets

IKKα: 8.97 μM; IKKβ: 3.59 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 48 mg/mL (199.75 mM); Water: Insoluble; Ethanol: 18 mg/mL (74.9 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

INH14 can be used to study its effects on inhibiting NF-κB, thereby providing insights into its potential therapeutic applications in cancer and inflammation.

Storage

Store at -20ºC.