IKK/IκB inhibitor LY2409881, Purity ≥98%

Synonym: 946518-60-1; LY2409881 trihydrochloride; LY2409881; LY2409881 (trihydrochloride); 2-(5-Chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide trihydrochloride; 2-(5-Chloro-2-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide trihydrochloride; IKK/IκB inhibitor

MDL: MFCD28900676
CAS Number: 946518-60-1
Compound CID: 68856073

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LY2409881, soluble in warmed DMSO and insoluble in water and ethanol, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK2.

Molecular Weight

594.43

Molecular Formula

C₂₄H₃₂Cl₄N₆OS

Targets

IKK2: 30 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 18 mg/mL (30.28 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

LY2409881 can be used to explore its role as an inhibitor of IKK2 in NF-κB signaling and its implications in cancer therapy.

Storage

Store at -20ºC.