IKK/IκB inhibitor TBK1/IKKε-IN-5, Purity ≥98%

Synonym: 1893397-65-3; TBK1/IKKepsilon-IN-5; TBK1/IKK|A-IN-5; 5-(4-((4-(4-(Oxetan-3-yl)piperazin-1-yl)phenyl)amino)-1,3,5-triazin-2-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile; 2-(Oxan-4-yloxy)-5-[4-[4-[4-(oxetan-3-yl)piperazin-1-yl]anilino]-1,3,5-triazin-2-yl]benzonitrile; IKK/IκB inhibitor

MDL: MFCD32067990
CAS Number: 1893397-65-3
Compound CID: 118979674

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TBK1/IKKε-IN-5, soluble in DMSO, water and ethanol, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses.

Molecular Weight

513.59

Molecular Formula

C₂₈H₃₁N₇O₃

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (17.52 mM); Water: <1 mg/mL; Ethanol: <1 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

TBK1/IKKε-IN-5 can be used to evaluate its dual inhibitory effects on TBK1 and IKKε, and their contributions to immune response modulation.