IKK/IκB inhibitor WS3, Purity ≥98%

Synonym: 1421227-52-2; WS3; N-(6-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide; IKK/IκB inhibitor

MDL: MFCD26142950
CAS Number: 1421227-52-2
Compound CID: 72551586

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WS3, soluble in warmed DMSO and warmed ethanol and insoluble in water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets EBP1 and IκB kinase.

Molecular Weight

569.58

Molecular Formula

C₂₈H₃₀F₃N₇O₃

Targets

EBP1; IκB kinase

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 88 mg/mL (154.49 mM); Water: Insoluble; Warmed ethanol: 70 mg/mL (122.89 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

WS3 can be explored for its potential as an anti-inflammatory agent through inhibition of specific signaling pathways.

Storage

Store at -20ºC.