Properties
Description
MCC950 sodium, soluble in water and ethanol and insoluble in DMSO, blocks the binding of interleukins (cytokines) to their corresponding receptors on the cell surface, thereby inhibiting the downstream signaling pathways. It targets NLRP3.
Molecular Formula
C20H23N2NaO5S
Solubility
DMSO: Insoluble; Water: 77 mg/mL (180.55 mM); Ethanol: 36 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
MCC950 sodium can be used to investigate its selective inhibition of the NLRP3 inflammasome in inflammation and autoimmune diseases.