Properties
Description
SC-144, soluble in DMSO and insoluble in ethanol and water, blocks the binding of interleukins (cytokines) to their corresponding receptors on the cell surface, thereby inhibiting the downstream signaling pathways. It targets gp130.
Molecular Formula
C16H11FN6O
Solubility
DMSO: 26 mg/mL (80.67 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SC-144 can be used for researching its cytotoxic effects in cancer therapy targeting GP130/STAT3 signaling pathways.