Integrin inhibitor, Cyclo (RGDyK) trifluoroacetate, Purity ≥98%

Synonym: 250612-42-1; Cyclic Arg-Gly-Asp-D-Tyr-Lys; Cyclo(RGDyK); 2-[(2S,5R,8S,11S)-8-(4-Aminobutyl)-11-[3-(diaminomethylideneamino)propyl]-5-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid; 2,2,2-trifluoroacetic acid

MDL: MFCD20134101
CAS Number: 250612-42-1
Compound CID: 129896716

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Cyclo (RGDyK) trifluoroacetate, soluble in DMSO, water and ethanol, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting integrin. It targets the αVβ3 integrin.

Molecular Weight

847.72

Molecular Formula

C₃₁H₄₃F₆N₉O₁₂

Targets

αvβ3 Integrin: 20 nM

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 97 mg/mL (114.42 mM); Water: 97 mg/mL (114.42 mM); Ethanol: 19 mg/mL (22.41 mM)

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Cyclo (RGDyK) trifluoroacetate is a cytoskeletal signaling inhibitor that can be used for its ability to disrupt integrin-mediated interactions.

Storage

Store at -20ºC, and keep desiccated.