Properties
Description
Lifitegrast, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting integrin.
Molecular Formula
C29H24Cl2N2O7S
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 98 mg/mL (159.22 mM); Water: insoluble; Ethanol: 20 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Lifitegrast is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of dry eye disease by blocking the interaction of integrin αLβ2 with its ligand, which reduces inflammation and improves symptoms.
Storage
Store at -20ºC, and keep desiccated.
