Integrin inhibitor, TR-14035, Purity ≥98%

Synonym: 232271-19-1; TR 14035; TR14035; (2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid

MDL: MFCD09970400
CAS Number: 232271-19-1
Compound CID: 9912743

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TR-14035, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting integrin. It targets the α4β1 and α4β7.

Molecular Weight

474.33

Molecular Formula

C₂₄H₂₁Cl₂NO₅

Targets

α4β1: 87 nM (IC₅₀); α4β7: 7 nM (IC₅₀)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 84 mg/mL (177.09 mM); Water: insoluble; Ethanol: 18 mg/mL (37.94 mM)

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

TR-14035 is a cytoskeletal signaling inhibitor that can be used for its effects on integrin-mediated cell adhesion and migration.

Storage

Store at -20ºC, and keep desiccated.