Properties
Description
TR-14035, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting integrin. It targets the α4β1 and α4β7.
Molecular Formula
C24H21Cl2NO5
Targets
α4β1: 87 nM (IC50); α4β7: 7 nM (IC50)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 84 mg/mL (177.09 mM); Water: insoluble; Ethanol: 18 mg/mL (37.94 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
TR-14035 is a cytoskeletal signaling inhibitor that can be used for its effects on integrin-mediated cell adhesion and migration.
Storage
Store at -20ºC, and keep desiccated.
