When cells proliferate normally, repeated cycles of cell division first lead to replicative senescence, and cells that successfully escape replicative senescence subsequently enter a compromised phase. However, cancer cells are able to escape replicative senescence and crisis, gaining the potential for unlimited replication. Telomerase dysfunction, oncogene activation, and persistent DNA damage can all stimulate cellular senescence. Among them, telomere attrition is a common cause of cell senescence. The occurrence and development of tumors must first achieve the maintenance of telomere length. CD BioGlyco can provide an analysis of the relationship between telomere function, oncogenes, and other factors that stimulate cellular senescence and the reprogramming of glucose metabolism.
There is a close relationship between the reprogramming of glucose metabolism in cancer cells and oncogene-induced senescence. For the relationship between the two, we can provide a series of detailed analysis services. If you want to know more information, please click to go to the service page.
NAD is an essential coenzyme for various metabolic pathways such as glycolysis and the tricarboxylic acid cycle. Shorter telomeres have been reported in several studies to play a role in NAD dysregulation, and the maintenance of telomeres may have links to the metabolic pathways in that NAD is involved. At the same time, mitochondria, as the main organelle of cellular energy metabolism, have also been reported to find that both telomere damage and mitochondrial dysfunction are features of cellular aging and there is a certain relationship between the two. Therefore, in order to further understand the interaction between glucose metabolism reprogramming and cellular aging, we provide analytical services to explore the relationship between telomere maintenance mechanisms and glucose metabolism reprogramming.
We can provide the following specific services based on the MOPCGM platform, including but not limited to:
CD BioGlyco can provide analytics services on the relationship between the reprogramming of glucose metabolism in cancer cells and aging, helping customers explore unknown areas of cancer research. Our experienced teams of scientists, researchers, and technicians provide a fast turnaround, and high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.
