Properties
Description
O6-Protected-5'-DMT-2'-OMe-G(iBu)-CE-phosphoramidite is a modified guanine (G) phosphoramidite compound containing O6 protection group, 5′-DMT and 2′-OMe modifications with isobutyl (G (iBu)) to enhance structural stability.
Molecular Formula
C57H70N7O11P
Form
White to off-white powder
Purity
≥98%, determined by HPLC.
Applications
O6-Protected-5'-DMT-2'-OMe-G(iBu)-CE-phosphoramidite can be used for the synthesis of antisense oligonucleotides with dominant properties, such as improved affinity and selectivity.