IRE1 inhibitor, 4μ8C, Purity ≥98%

Synonym: 14003-96-4; 7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde; 4mu8C; 7-Hydroxy-4-methyl-2-oxochromene-8-carbaldehyde; 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde; 7-Hydroxy-4-methyl-2-oxochromene-8-carbaldehyde

MDL: MFCD12027255
CAS Number: 14003-96-4
Compound CID: 12934390

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

4μ8C, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1. It targets the IRE1 Rnase.

Molecular Weight

204.18

Molecular Formula

C₁₁H₈O₄

Targets

IRE1 Rnase: 76 nM

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 17 mg/mL (83.26 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 40% PEG300 + 5% Tween80 + 50% ddH₂O, 0.4 mg/mL

Applications

4μ8C is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of inflammation and cancer.