IRE1 inhibitor, APY29, Purity ≥98%

Synonym: 1216665-49-4; APY 29; Apy-29; APY29 Hydrochloride salt; 2,4-Pyrimidinediamine, N2-1H-benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-; 2-N-(3H-Benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine; 2-N-(3H-Benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

MDL: MFCD28023582
CAS Number: 1216665-49-4
Compound CID: 42627755

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

APY29, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1.

Molecular Weight

332.36

Molecular Formula

C₁₇H₁₆N₈

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 27 mg/mL (81.24 mM); Water: insoluble; Ethanol: insoluble

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

APY29 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of neurodegenerative diseases and cancer.

Storage

Store at -20ºC, and keep desiccated.