IRE1 inhibitor, KIRA6, Purity ≥98%

Synonym: 1589527-65-0; KIRA-6; 1-(4-(8-Amino-3-(tert-butyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea; 1-(4-(8-Amino-3-tert-butylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea; 1-[4-(8-Amino-3-tert-butylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea

CAS Number: 1589527-65-0
Compound CID: 73425700

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

KIRA6, soluble in DMSO and ethanol and insoluble in water, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1.

Molecular Weight

518.53

Molecular Formula

C₂₈H₂₅F₃N₆O

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 59 mg/mL (113.78 mM); Water: insoluble; Ethanol: 59 mg/mL (113.78 mM)

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

KIRA6 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of disorders like Alzheimer’s disease.

Storage

Store at -20ºC, and keep desiccated.