IRE1 inhibitor, MKC3946, Purity ≥98%

Synonym: 1093119-54-0; MKC 3946; MKC-3946; 2-Hydroxy-6-(5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl)-1-naphthaldehyde; 2-hydroxy-6-[5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl]naphthalene-1-carbaldehyde; 2-Hydroxy-6-[5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl]naphthalene-1-carbaldehyde

CAS Number: 1093119-54-0
Compound CID: 59599728

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MKC3946, soluble in DMSO and ethanol and insoluble in water, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1.

Molecular Weight

380.46

Molecular Formula

C₂₁H₂₀N₂O₃S

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 35 mg/mL (91.99 mM); Water: insoluble; Ethanol: 3 mg/mL (7.88 mM)

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

MKC3946 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of various cancers and autoimmune diseases, as BTK is involved in B-cell signaling pathways.

Storage

Store at -20ºC, and keep desiccated.