IRE1 inhibitor, MKC8866, Purity ≥98%

Synonym: 1338934-59-0; MKC-8866; MKC 8866; IRE1-IN-8866; IRE1IN8866; IRE1 IN 8866; IRE1-IN8866; IRE1-IN 8866; IRE1IN-8866; IRE1IN 8866; 7-Hydroxy-6-methoxy-4-methyl-3-(2-morpholin-4-yl-2-oxoethyl)-2-oxochromene-8-carbaldehyde

CAS Number: 1338934-59-0
Compound CID: 89542346

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MKC8866, soluble in DMSO, water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1.

Molecular Weight

361.35

Molecular Formula

C₁₈H₁₉NO₇

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 3 mg/mL (8.3 mM); Water: <1 mg/mL; Ethanol: <1 mg/mL

Applications

MKC8866 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancer and neurodegenerative diseases, as HDAC6 is involved in regulating protein degradation and cell stress responses.