Properties
Description
STF-083010, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1.
Molecular Formula
C15H11NO3S2
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 54 mg/mL (170.14 mM); Water: insoluble; Ethanol: insoluble; In vivo: 2% DMSO + 40% PEG 300 + 5% Tween80 + ddH2O, 1 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
STF-083010 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of Angelman syndrome, a genetic disorder caused by the loss of function of the UBE3A gene.
Storage
Store at -20ºC, and keep desiccated.
