IRE1 inhibitor, STF-083010, Purity ≥98%

Synonym: 307543-71-1; STF083010; STF 083010; (E)-N-((2-Hydroxynaphthalen-1-yl)methylene)thiophene-2-sulfonamide; (NE)-N-[(2-Hydroxynaphthalen-1-yl)methylidene]thiophene-2-sulfonamide

CAS Number: 307543-71-1
Compound CID: 135398515

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

STF-083010, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting IRE1.

Molecular Weight

317.38

Molecular Formula

C₁₅H₁₁NO₃S₂

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 54 mg/mL (170.14 mM); Water: insoluble; Ethanol: insoluble; In vivo: 2% DMSO + 40% PEG 300 + 5% Tween80 + ddH₂O, 1 mg/mL

Applications

STF-083010 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of Angelman syndrome, a genetic disorder caused by the loss of function of the UBE3A gene.