Provide Iron Dextran Analysis on the Practicable Principle

Iron dextran is a low molecular weight iron hydroxide complex and is an effective iron supplement. Iron dextran is taken up by macrophages via endocytosis and releases ferrous iron (Fe²⁺). Upon entering the bloodstream, ferrous iron is immediately oxidized to ferric iron (Fe³⁺) by ceruloplasmin, which binds to transferrin and is transported throughout the body for utilization. CD BioGlyco provides a comprehensive analysis including iron dextran analysis, iron dextran tablet analysis, and iron dextran injection analysis services. Our laboratory has accumulated rich experience in Pharmaceutical Analysis.

• Identification test
  Our researchers provide simple and rapid identification services. To detect changes in color and precipitation for the determination of iron dextran, add ammonia solution or anthrone solution to the sample solution. We provide accurate Fe content testing service by sodium thiosulfate titration. Where each 1ml of sodium thiosulfate titrant consumed indicates the presence of 5.585 mg of Fe. In addition, we provide free iron rapid identification service, chloride content determination service, loss on drying to constant weight, and metal content determination services.
• Molecular weight determination
  We determine the molecular weight distribution of iron dextran by size exclusion chromatography (SEC). The molecular weight distribution of the samples is determined by comparing the retention times of different molecular weight controls of iron dextran (peak molecular weights of 2000 to 60,000) with the samples to be tested.
  Moreover, we provide high-performance liquid chromatography (HPLC) analysis, thin-layer chromatography (TLC) analysis, mass spectrometry (MS) analysis, and nuclear magnetic resonance (NMR) spectra analysis services.
• Special test
  For iron dextran tablets, we provide a high-sensitive dissolution rate analysis service by atomic absorption spectrophotometry.
  For iron dextran injection, we analyze the unabsorbed Fe content at the injection site by constructing an animal model. Our researchers have proven experience in raising animals, constructing models, and administering drugs by injection. The administered samples and control samples are measured by UV spectrophotometer. During the administration period, our researchers regularly observe and record the animal status e.g. body weight, skin status, color changes at the injection site, etc. Moreover, we perform gel or photometrics on qualitative or semi-quantitative endotoxin.

Fig.1 Schematic diagram of iron dextran analysis service. (CD BioGlyco)

Publication Data

Applications

• An in-depth analysis of iron dextran facilitates the development of iron supplementation agents and further promotes the development of studies on the safety and efficacy of iron deficiency anemia in children.
• Iron dextran is a new target for clinical research in models with iron deficiency sepsis.
• Metabolic analysis of iron dextran plays a key role in studying VD3 activation and metabolic pathways.

Advantages of Us

• We provide clients with raw data, test conditions, and professional data analysis reports.
• According to the measurement needs of clients, our professional staff recommends the most appropriate project analysis for you.
• Our rigorous and conscientious service attitude and efficient service quality have been praised by clients all over the world.

CD BioGlyco has skilled operators and knowledgeable scientists to drive client projects forward. Our research team provides clients with comprehensive Pharmaceutical and Biological analysis services using advanced analysis systems. We are your ideal partner. Please feel free to contact us.