Iron sucrose injection is a pharmaceutical intervention employed for the management of iron deficiency, particularly when oral iron supplements prove to be ineffective or poorly tolerated. This medication is frequently utilized in the alleviation of anemia symptoms among patients afflicted with chronic kidney disease. CD BioGlyco offers expert iron sucrose injection analysis services, leveraging our extensive experience in Pharmaceutical Analysis to support clients in advancing their drug discovery process.
Fig.1 Iron sucrose injection analysis service. (CD BioGlyco)
Technology: Radioisotope labeling techniques, Stable isotope labeling techniques, Calculations of total iron transfer
IF: 5.4
Published: 2011
Journals: Pharmaceutics
Results: The main focus of this paper is on the pharmacokinetics and pharmacodynamics of iron preparations. Pharmacokinetics focuses on the bioavailability of iron preparations, i.e., the rate and extent of absorption of the active substance or active moiety from the drug form and its availability at the site of action. Pharmacodynamics focuses on the pharmacodynamic properties of iron preparations, including reactivity with transferrin, risk of adverse events, and guidance on possible dosing regimens. The article describes several experimental methods to assess and compare the absorption and efficacy of iron preparations, including radioisotope labeling techniques, stable isotope labeling techniques, and calculations of total iron transfer. The article also discusses the pharmacokinetic and pharmacodynamic characteristics of oral and intravenous iron preparations, as well as the oxidative stress and adverse clinical consequences that may result from high doses of oral iron or rapid-release intravenous iron.
Fig.2 Schematic representation of iron metabolism. (Geisser & Burckhardt, 2011)
At CD BioGlyco, we provide a comprehensive and reliable solution for evaluating the quality of iron sucrose injections. Our team of experienced scientists and technicians utilizes state-of-the-art analytical techniques to assess various parameters. If you would like more information about our services, please feel free to contact us.
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