Isocitrate dehydrogenase (IDH) inhibitor, DS-1001b, Purity ≥98%

Synonym: 1898207-64-1; 2-Methylpropan-2-amine (E)-3-(1-(5-(2-fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)isoxazole-4-carbonyl)-3-methyl-1H-indol-4-yl)acrylate; Safusidenib erbumine; (E)-3-[1-[5-(2-Fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)-1,2-oxazole-4-carbonyl]-3-methylindol-4-yl]prop-2-enoic acid; 2-methylpropan-2-amine; Isocitrate dehydrogenase (IDH) inhibitor

MDL: MFCD32263044
CAS Number: 1898207-64-1
Compound CID: 139600317

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DS-1001b is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting isocitrate dehydrogenase (IDH). The molecular weight of the compound is 608.92, and its molecular formula is C₂₉H₂₉Cl₃FN₃O₄.

Molecular Weight

608.92

Molecular Formula

C₂₉H₂₉Cl₃FN₃O₄

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Identity

Confirmed by NMR/HPLC/MS.

Applications

DS-1001b can be studied extensively for its potential therapeutic applications in the treatment of acute myeloid leukemia (AML) and other IDH2-mutant cancers.