Properties
Description
Olutasidenib, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting isocitrate dehydrogenase (IDH). The molecular weight of the compound is 354.79, and its molecular formula is C18H15ClN4O2.
Molecular Formula
C18H15ClN4O2
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 70 mg/mL (197.29 mM); Water: insoluble; Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Olutasidenib can be used for its ability to inhibit the mutated IDH1 enzyme and counteract the oncogenic effects of its aberrant activity.