Isocitrate dehydrogenase (IDH) inhibitor, Vorasidenib, Purity ≥98%

Synonym: 1644545-52-7; AG-881; AG 881; AG881; 6-(6-Chloropyridin-2-yl)-2-N,4-N-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine; Isocitrate dehydrogenase (IDH) inhibitor

CAS Number: 1644545-52-7
Compound CID: 117817422

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Vorasidenib, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting isocitrate dehydrogenase (IDH). The molecular weight of the compound is 414.74, and its molecular formula is C₁₄H₁₃ClF₆N₆.

Molecular Weight

414.74

Molecular Formula

C₁₄H₁₃ClF₆N₆

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 75 mg/mL (180.83 mM); Water: insoluble; Ethanol: 75 mg/mL (180.83 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Vorasidenib can be studied extensively for its potential therapeutic applications in the treatment of various IDH-mutant cancers, including gliomas and AML.