Istradefylline

Synonym: 155270-99-8; KW-6002; Nouriast

CAS Number: 155270-99-8
Compound CID: 5311037

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Istradefylline (KW-6002), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets adenosine A2A receptor.

Molecular Weight

384.4

Molecular Formula

C₂₀H₂₄N₄O₄

Targets

Adenosine A2A receptor: 2.2 nM (Ki)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 5 mg/mL (13 mM); Water: insoluble; Ethanol: insoluble

Applications

Istradefylline (KW-6002) can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.