Properties
Description
Istradefylline (KW-6002), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets adenosine A2A receptor.
Molecular Formula
C20H24N4O4
Targets
Adenosine A2A receptor: 2.2 nM (Ki)
Solubility
DMSO: 5 mg/mL (13 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Istradefylline (KW-6002) can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.
Storage
Store at -20°C, and keep desiccated.
