Properties
Description
IT1t inhibits autophagy, through multiple signaling pathways. It targets CXCL12/CXCR4, HIV-1 (X4), and HIV-1 (X4).
Molecular Formula
C21H34N4S2
Targets
CXCL12/CXCR4: 2.1 nM; HIV-1 (X4): 14.2 nM (IC50, in MT-4 cells); HIV-1 (X4): 19 nM (IC50, in PBMCs)
Applications
IT1t can be used for its ability to inhibit CXCL12/CXCR4 interaction.
